America's Compounding Center says this about Niacine (B3):
"Niacin, also known as nicotinic acid, nicotinamide or vitamin B3, is a complex B vitamin. Niacin is used to treat patients with niacin deficiency, known as pellagra, which may be due to poor dietary intake, aging, malabsorption syndromes, or alcoholism. Classic symptoms associated with pellagra include inflammation and irritation of the skin, mental confusion, and diarrhea. Patients commonly develop a rash with darkening or thickening of the skin on the face. Niacin is found in lean meats, poultry, grains, eggs, fish, milk and legumes (such as beans, peas and peanuts). The recommended dose of niacin for mitochondrial disorders ranges from 50-100mg by mouth daily, according to the UMDF. Side effects associated with niacin supplementation include stomach discomfort, flushing of the upper body (particularly face and neck), headache, and liver problems. "