Here is what America's Compounding Center says about Quinine:
"Quinine, which is derived from the herb Cinchona succirubra, was historically applied topically to treat hemorroids and varicose veins. It can be prescribed by a doctor as the doctor as the brand-name medication Qualaquin to treat malaria and the tick-borne illness babesiosis. It is also taken by patients to prevent or treat nighttime leg cramps, and can be used to alleviate leg and muscle cramps in patients with mitochondrial disease. Quinine is taken at low doses of 200-300 mg once every evening for leg cramps, but is used in higher doses for the treatment of malaria and babesiosis. Quinine can cause serious side effects, including a condition called cinchonism, which may result in severe headaches, abdominal discomfort, convulsions, and vision problems. Quinine can also cause severe allergic reactions, hearing problems and ringing in the ears, fever, chills, blood abnormalities, confusion, dizziness, changes in heart rate and/or rhythm, jaundice, and kidney or liver problems."